Effects of α-Thalassemia on Pharmacokinetics of the Antimalarial Agent Artesunate

Thalassemia is common in Southeast Asia, where artemisinin derivatives are frequently used in the treatment of malaria. It has been previously reported that artemisinin derivatives can be concentrated by uninfected thalassemic erythrocytes in vitro but not by normal erythrocytes. As a follow-up to t...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ittarat, Wanida, Looareesuwan, Sornchai, Pootrakul, Pensri, Sumpunsirikul, Petchmanee, Vattanavibool, Phantip, Meshnick, Steven R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2332
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