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Structure-Function Studies of Ser-289 in the Class C β-Lactamase from Enterobacter cloacae P99

Site-directed mutagenesis of Ser-289 of the class C β-lactamase from Enterobacter cloacae P99 was performed to investigate the role of this residue in β-lactam hydrolysis. This amino acid lies near the active site of the enzyme, where it can interact with the C-3 substituent of cephalosporins. Kinet...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Trépanier, Sonia, Knox, James R., Clairoux, Natalie, Sanschagrin, François, Levesque, Roger C., Huletsky, Ann
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC89158/
https://ncbi.nlm.nih.gov/pubmed/10049265
Tagiau: Ychwanegu Tag
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