Structure-Function Studies of Ser-289 in the Class C β-Lactamase from Enterobacter cloacae P99
Site-directed mutagenesis of Ser-289 of the class C β-lactamase from Enterobacter cloacae P99 was performed to investigate the role of this residue in β-lactam hydrolysis. This amino acid lies near the active site of the enzyme, where it can interact with the C-3 substituent of cephalosporins. Kinet...
Zapisane w:
| Wydane w: | Antimicrob Agents Chemother |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
1999
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.543 |
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