Influences of Urinary pH on Ciprofloxacin Pharmacokinetics in Humans and Antimicrobial Activity In Vitro versus Those of Sparfloxacin

The impact of acidification and alkalinization of urine on the pharmacokinetics of ciprofloxacin was investigated after single 200-mg oral doses were administered to nine healthy male volunteers. In addition, the effect of human urine on the MICs of ciprofloxacin and sparfloxacin against some common...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Kamberi, Marika, Tsutsumi, Kimiko, Kotegawa, Tsutomu, Kawano, Koichi, Nakamura, Koichi, Niki, Yoshihito, Nakano, Shigeyuki
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1999
Teme:	Pharmacology
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.525
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