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Pharmacokinetics and Urinary Excretion of Amikacin in Low-Clearance Unilamellar Liposomes after a Single or Repeated Intravenous Administration in the Rhesus Monkey

Liposomal aminoglycosides have been shown to have activity against intracellular infections, such as those caused by Mycobacterium avium. Amikacin in small, low-clearance liposomes (MiKasome) also has curative and prophylactic efficacies against Pseudomonas aeruginosa and Klebsiella pneumoniae. To d...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Fielding, Robert M., Moon-Mcdermott, Lotus, Lewis, Ramilla O., Horner, Michelle J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.503
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