Multiple-dose pharmacokinetics and safety of oral amifloxacin in healthy volunteers.

The multiple-dose pharmacokinetics and safety of amifloxacin, a new fluoroquinolone antibacterial agent, were evaluated in healthy male volunteers. Amifloxacin was administered orally at 200, 400, or 600 mg every 12 h (q12h) and 400, 600, or 800 mg every 8 h (q8h) for 10 days. An additional dose was...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Cook, J A, Silverman, M H, Schelling, D J, Nix, D E, Schentag, J J, Brown, R R, Stroshane, R M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2393295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.974
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