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Pharmacodynamics of Trovafloxacin, Ofloxacin, and Ciprofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model

An in vitro pharmacokinetic model was used to simulate the pharmacokinetics of trovafloxacin, ofloxacin, and ciprofloxacin in human serum and to compare their pharmacodynamics against eight Streptococcus pneumoniae strains. The MICs of ofloxacin and ciprofloxacin ranged from 1 to 2 μg/ml. Trovafloxa...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Lister, Philip D., Sanders, Christine C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1118
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