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Pharmacodynamics of Levofloxacin and Ciprofloxacin in a Murine Pneumonia Model: Peak Concentration/MIC versus Area under the Curve/MIC Ratios

During the last decade some studies have shown that the area under the curve (AUC)/MIC ratio is the pharmacodynamic index that best predicts the efficacies of quinolones, while other studies suggest that the predictive value of the peak concentration/MIC (peak/MIC) ratio is superior to the AUC/MIC r...

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Bibliografiske detaljer
Main Authors: Scaglione, F., Mouton, J. W., Mattina, R., Fraschini, F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC182632/
https://ncbi.nlm.nih.gov/pubmed/12936969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2749-2755.2003
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