Pharmacodynamics of Levofloxacin and Ciprofloxacin in a Murine Pneumonia Model: Peak Concentration/MIC versus Area under the Curve/MIC Ratios

During the last decade some studies have shown that the area under the curve (AUC)/MIC ratio is the pharmacodynamic index that best predicts the efficacies of quinolones, while other studies suggest that the predictive value of the peak concentration/MIC (peak/MIC) ratio is superior to the AUC/MIC r...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Scaglione, F., Mouton, J. W., Mattina, R., Fraschini, F.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2749-2755.2003
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