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Interplay between Chromosomal β-Lactamase and the MexAB-OprM Efflux System in Intrinsic Resistance to β-Lactams in Pseudomonas aeruginosa

We investigated the role of chromosomal β-lactamase and the MexAB-OprM efflux system in intrinsic resistance to β-lactams in Pseudomonas aeruginosa. Determination of the susceptibilities of a series of isogenic mutants with impaired production of the β-lactamase and the efflux system to 16 β-lactams...

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Dettagli Bibliografici
Autori principali: Masuda, Nobuhisa, Gotoh, Naomasa, Ishii, Chie, Sakagawa, Eiko, Ohya, Satoshi, Nishino, Takeshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC89089/
https://ncbi.nlm.nih.gov/pubmed/9925544
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