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Activities of Newer Fluoroquinolones against Streptococcus pneumoniae Clinical Isolates Including Those with Mutations in the gyrA, parC, and parE Loci

Resistance to fluoroquinolone (FQ) antibiotics in Streptococcus pneumoniae has been attributed primarily to specific mutations in the genes for DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE). Resistance to some FQs can result from a single mutation in one or more of the genes encodi...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Jorgensen, J. H., Weigel, L. M., Ferraro, M. J., Swenson, J. M., Tenover, F. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925527/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.329
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