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Activities of Newer Fluoroquinolones against Streptococcus pneumoniae Clinical Isolates Including Those with Mutations in the gyrA, parC, and parE Loci

Resistance to fluoroquinolone (FQ) antibiotics in Streptococcus pneumoniae has been attributed primarily to specific mutations in the genes for DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE). Resistance to some FQs can result from a single mutation in one or more of the genes encodi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Jorgensen, J. H., Weigel, L. M., Ferraro, M. J., Swenson, J. M., Tenover, F. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89072/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925527/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.329
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