ParC and GyrA May Be Interchangeable Initial Targets of Some Fluoroquinolones in Streptococcus pneumoniae

To evaluate the role of known topoisomerase IV and gyrase mutations in the fluoroquinolone (FQ) resistance of Streptococcus pneumoniae, we transformed susceptible strain R6 with PCR-generated fragments encompassing the quinolone resistance-determining regions (QRDRs) of parC or gyrA from different r...

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Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Varon, Emmanuelle, Janoir, Claire, Kitzis, Marie-Dominique, Gutmann, Laurent
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1999
Ämnen:	Mechanisms of Resistance
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.302
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