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ParC and GyrA May Be Interchangeable Initial Targets of Some Fluoroquinolones in Streptococcus pneumoniae

To evaluate the role of known topoisomerase IV and gyrase mutations in the fluoroquinolone (FQ) resistance of Streptococcus pneumoniae, we transformed susceptible strain R6 with PCR-generated fragments encompassing the quinolone resistance-determining regions (QRDRs) of parC or gyrA from different r...

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Bibliografski detalji
Glavni autori: Varon, Emmanuelle, Janoir, Claire, Kitzis, Marie-Dominique, Gutmann, Laurent
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89068/
https://ncbi.nlm.nih.gov/pubmed/9925523
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