Identification of an Efflux Pump Gene, pmrA, Associated with Fluoroquinolone Resistance in Streptococcus pneumoniae

An open reading frame (ORF) homologous to norA was insertionally inactivated with cat in a fluoroquinolone-resistant pneumococcus with an efflux phenotype; this inactivation caused reversion to drug sensitivity. The ORF product has 24% amino acid sequence identity each to NorA and Bmr, which suggest...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gill, Martin J., Brenwald, Nigel P., Wise, Richard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869592/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.187
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!