ADP-Ribosylation as an Intermediate Step in Inactivation of Rifampin by a Mycobacterial Gene
Mycobacterium smegmatis DSM43756 inactivates rifampin, and the inactivated antibiotic product recovered from culture medium was ribosylated on the 23-OH group. To study this process, the gene responsible for the inactivation was expressed at high levels by the lac promoter in Escherichia coli confer...
Uloženo v:
| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.1.181 |
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