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Insertion of a Telomere Repeat Sequence into a Mammalian Gene Causes Chromosome Instability

Telomere repeat sequences cap the ends of eucaryotic chromosomes and help stabilize them. At interstitial sites, however, they may destabilize chromosomes, as suggested by cytogenetic studies in mammalian cells that correlate interstitial telomere sequence with sites of spontaneous and radiation-ind...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Mol Cell Biol
Ngā kaituhi matua: Kilburn, April E., Shea, Martin J., Sargent, R. Geoffrey, Wilson, John H.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis 2001
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88786/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11113187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.1.126-135.2001
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