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Promotion of Cell Cycle Progression by Basic Helix-Loop-Helix E2A

Normal B-cell development requires the E2A gene and its encoded transcription factors E12 and E47. Current models predict that E2A promotes cell differentiation and inhibits G(1) cell cycle progression. The latter raises the conundrum of how B cells proliferate while expressing high levels of E2A pr...

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Hlavní autoři: Zhao, Fang, Vilardi, Antonina, Neely, Robert J., Choi, John Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87370/
https://ncbi.nlm.nih.gov/pubmed/11509675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6346-6357.2001
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