Promotion of Cell Cycle Progression by Basic Helix-Loop-Helix E2A

Normal B-cell development requires the E2A gene and its encoded transcription factors E12 and E47. Current models predict that E2A promotes cell differentiation and inhibits G(1) cell cycle progression. The latter raises the conundrum of how B cells proliferate while expressing high levels of E2A pr...

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Bibliografiske detaljer
Main Authors: Zhao, Fang, Vilardi, Antonina, Neely, Robert J., Choi, John Kim
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87370/
https://ncbi.nlm.nih.gov/pubmed/11509675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6346-6357.2001
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