Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar

In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. Here we define a homologous system in Drosophila melanogaster, and we characterize its activity in vivo during development....

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Detalhes bibliográficos
Main Authors: Lavista-Llanos, Sofía, Centanin, Lázaro, Irisarri, Maximiliano, Russo, Daniela M., Gleadle, Jonathan M., Bocca, Silvia N., Muzzopappa, Mariana, Ratcliffe, Peter J., Wappner, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134029/
https://ncbi.nlm.nih.gov/pubmed/12215541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6842-6853.2002
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