Relationship between Mutations in Dihydropteroate Synthase of Pneumocystis carinii f. sp. hominis Isolates in Japan and Resistance to Sulfonamide Therapy

We examined mutations in the dihydropteroate synthase (DHPS) genes of Pneumocystis carinii f. sp. hominis (P. carinii) strains isolated from 24 patients with P. carinii pneumonia (PCP) in Japan. DHPS mutations were identified at amino acid positions 55 and/or 57 in isolates from 6 (25.0%) of 24 pati...

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Detaylı Bibliyografya
Yayımlandı:	J Clin Microbiol
Asıl Yazarlar:	Takahashi, Takashi, Hosoya, Noriaki, Endo, Tokiomi, Nakamura, Tetsuya, Sakashita, Hiroyuki, Kimura, Kyoko, Ohnishi, Kenji, Nakamura, Yoshikazu, Iwamoto, Aikichi
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2000
Konular:	Mycology
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.38.9.3161-3164.2000
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Relationship between Mutations in Dihydropteroate Synthase of Pneumocystis carinii f. sp. hominis Isolates in Japan and Resistance to Sulfonamide Therapy

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