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Nuclear Localization of CBF1 Is Regulated by Interactions with the SMRT Corepressor Complex

The CSL family protein CBF1 is a nuclear mediator of Notch signaling and has been predicted to contain an N-terminal nuclear localization signal in exon 4. Surprisingly, we found that CBF1 carrying mutations at codon 233 or 249 within exon 7 was restricted to the cytoplasm. In mammalian and yeast tw...

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Udgivet i:Mol Cell Biol
Principais autores: Zhou, Sifang, Hayward, S. Diane
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11509665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.18.6222-6232.2001
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