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Nuclear Localization of CBF1 Is Regulated by Interactions with the SMRT Corepressor Complex
The CSL family protein CBF1 is a nuclear mediator of Notch signaling and has been predicted to contain an N-terminal nuclear localization signal in exon 4. Surprisingly, we found that CBF1 carrying mutations at codon 233 or 249 within exon 7 was restricted to the cytoplasm. In mammalian and yeast tw...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87339/ https://ncbi.nlm.nih.gov/pubmed/11509665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6222-6232.2001 |
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