DNA Damage-Induced G(1) Arrest in Hematopoietic Cells Is Overridden following Phosphatidylinositol 3-Kinase-Dependent Activation of Cyclin-Dependent Kinase 2

Exposure of hematopoietic cells to DNA-damaging agents induces p53-independent cell cycle arrest at a G(1) checkpoint. Previously, we have shown that this growth arrest can be overridden by cytokine growth factors, such as erythropoietin or interleukin-3, through activation of a phosphatidylinositol...

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Detalhes bibliográficos
Main Authors: Eapen, Alex K., Henry, Matthew K., Quelle, Dawn E., Quelle, Frederick W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87328/
https://ncbi.nlm.nih.gov/pubmed/11509654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6113-6121.2001
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