Signal Pathways Which Promote Invasion and Metastasis: Critical and Distinct Contributions of Extracellular Signal-Regulated Kinase and Ral-Specific Guanine Exchange Factor Pathways

Approximately 50% of metastatic tumors contain Ras mutations. Ras proteins can activate at least three downstream signaling cascades mediated by the Raf–MEK–extracellular signal-regulated kinase family, phosphatidylinositol-3 (PI3) kinase, and Ral-specific guanine nucleotide exchange factors (RalGEF...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ward, Yvona, Wang, Warner, Woodhouse, Elisa, Linnoila, Ilona, Liotta, Lance, Kelly, Kathleen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87314/
https://ncbi.nlm.nih.gov/pubmed/11486034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5958-5969.2001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky