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Identification of Receptor and Heparin Binding Sites in Fibroblast Growth Factor 4 by Structure-Based Mutagenesis

Fibroblast growth factors (FGFs) comprise a large family of multifunctional, heparin-binding polypeptides that show diverse patterns of interaction with a family of receptors (FGFR1 to -4) that are subject to alternative splicing. FGFR binding specificity is an essential mechanism in the regulation...

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Udgivet i:Mol Cell Biol
Principais autores: Bellosta, Paola, Iwahori, Akiyo, Plotnikov, Alexander N., Eliseenkova, Anna V., Basilico, Claudio, Mohammadi, Moosa
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87313/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11486033/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.17.5946-5957.2001
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