Identification of Receptor and Heparin Binding Sites in Fibroblast Growth Factor 4 by Structure-Based Mutagenesis

Fibroblast growth factors (FGFs) comprise a large family of multifunctional, heparin-binding polypeptides that show diverse patterns of interaction with a family of receptors (FGFR1 to -4) that are subject to alternative splicing. FGFR binding specificity is an essential mechanism in the regulation...

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Main Authors: Bellosta, Paola, Iwahori, Akiyo, Plotnikov, Alexander N., Eliseenkova, Anna V., Basilico, Claudio, Mohammadi, Moosa
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC87313/
https://ncbi.nlm.nih.gov/pubmed/11486033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5946-5957.2001
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