Identification and Functional Characterization of Neo-Poly(A) Polymerase, an RNA Processing Enzyme Overexpressed in Human Tumors

Poly(A) polymerase (PAP) plays an essential role in polyadenylation of mRNA precursors, and it has long been thought that mammalian cells contain only a single PAP gene. We describe here the unexpected existence of a human PAP, which we call neo-PAP, encoded by a previously uncharacterized gene. cDN...

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Main Authors: Topalian, Suzanne L., Kaneko, Syuzo, Gonzales, Monica I., Bond, Gareth L., Ward, Yvona, Manley, James L.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
主題:
Gene Expression
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC87282/
https://ncbi.nlm.nih.gov/pubmed/11463842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5614-5623.2001
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