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Human capping enzyme promotes formation of transcriptional R loops in vitro

Cap formation is the first step of pre-mRNA processing in eukaryotic cells. Immediately after transcription initiation, capping enzyme (CE) is recruited to RNA polymerase II (Pol II) by the phosphorylated carboxyl-terminal domain of the Pol II largest subunit (CTD), allowing cotranscriptional cappin...

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Detalles Bibliográficos
Main Authors: Kaneko, Syuzo, Chu, Chun, Shatkin, Aaron J., Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077024/
https://ncbi.nlm.nih.gov/pubmed/17978174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708866104
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