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Structure of the guanylyltransferase domain of human mRNA capping enzyme
The enzyme guanylyltransferase (GTase) plays a central role in the three-step catalytic process of adding an (m7)GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs). The 5′-mRNA capping process is functionally and evolutionarily conserved from unicellular organisms to human. However, the GTase...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121809/ https://ncbi.nlm.nih.gov/pubmed/21636784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106610108 |
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