Structure of the guanylyltransferase domain of human mRNA capping enzyme

The enzyme guanylyltransferase (GTase) plays a central role in the three-step catalytic process of adding an (m7)GpppN cap cotranscriptionally to nascent mRNA (pre-mRNAs). The 5′-mRNA capping process is functionally and evolutionarily conserved from unicellular organisms to human. However, the GTase...

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Bibliografiska uppgifter
Huvudupphovsmän: Chu, Chun, Das, Kalyan, Tyminski, James R., Bauman, Joseph D., Guan, Rongjin, Qiu, Weihua, Montelione, Gaetano T., Arnold, Eddy, Shatkin, Aaron J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121809/
https://ncbi.nlm.nih.gov/pubmed/21636784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106610108
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