Protein Kinase C-δ Regulates Thrombin-Induced ICAM-1 Gene Expression in Endothelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

The procoagulant thrombin promotes the adhesion of polymorphonuclear leukocytes to endothelial cells by a mechanism involving expression of intercellular adhesion molecule 1 (ICAM-1) via an NF-κB-dependent pathway. We now provide evidence that protein kinase C-δ (PKC-δ) and the p38 mitogen-activated...

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Detalhes bibliográficos
Main Authors: Rahman, Arshad, Anwar, Khandaker N., Uddin, Shahab, Xu, Ning, Ye, Richard D., Platanias, Leonidas C., Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87277/
https://ncbi.nlm.nih.gov/pubmed/11463837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5554-5565.2001
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