High-Copy-Number Expression of Sub2p, a Member of the RNA Helicase Superfamily, Suppresses hpr1-Mediated Genomic Instability

We report on a novel role for a pre-mRNA splicing component in genome stability. The Hpr1 protein, a component of an RNA polymerase II complex and required for transcription elongation, is also required for genome stability. Deletion of HPR1 results in a 1,000-fold increase in genome instability, de...

Descripció completa

Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Fan, Hua-Ying, Merker, Robert J., Klein, Hannah L.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2001
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11463828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.16.5459-5470.2001
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!