High-Copy-Number Expression of Sub2p, a Member of the RNA Helicase Superfamily, Suppresses hpr1-Mediated Genomic Instability
We report on a novel role for a pre-mRNA splicing component in genome stability. The Hpr1 protein, a component of an RNA polymerase II complex and required for transcription elongation, is also required for genome stability. Deletion of HPR1 results in a 1,000-fold increase in genome instability, de...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
2001
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11463828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.16.5459-5470.2001 |
| الوسوم: |
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