The Multisubstrate Adapter Gab1 Regulates Hepatocyte Growth Factor (Scatter Factor)–c-Met Signaling for Cell Survival and DNA Repair

Hepatocyte growth factor (scatter factor) (HGF/SF) is a pleiotrophic mediator of epithelial cell motility, morphogenesis, angiogenesis, and tumorigenesis. HGF/SF protects cells against DNA damage by a pathway from its receptor c-Met to phosphatidylinositol 3-kinase (PI3K) to c-Akt, resulting in enha...

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Dettagli Bibliografici
Autori principali: Fan, Saijun, Ma, Yong Xian, Gao, Min, Yuan, Ren-Qi, Meng, Qinghui, Goldberg, Itzhak D., Rosen, Eliot M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC87224/
https://ncbi.nlm.nih.gov/pubmed/11438654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4968-4984.2001
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