Role of Src Signal Transduction Pathways in Scatter Factor-mediated Cellular Protection

Scatter factor (SF) (hepatocyte growth factor) is a pleiotrophic cytokine that accumulates in tumors, where it may induce invasion, angiogenesis, and chemoresistance. We have studied the mechanisms by which SF and its receptor (c-Met) protect cells against the DNA-damaging agent adriamycin (ADR) as...

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Bibliographic Details
Main Authors: Fan, Saijun, Meng, Qinghui, Laterra, John J., Rosen, Eliot M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658051/
https://ncbi.nlm.nih.gov/pubmed/19047046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807497200
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