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A Quantification of Pathway Components Supports a Novel Model of Hedgehog Signal Transduction

The secreted protein Hedgehog (Hh) plays a critical instructional role during metazoan development. In Drosophila, Hh signaling is interpreted by a set of conserved, downstream effectors that differentially localize and interact to regulate the stability and activity of the transcription factor Cubi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Farzan, Shohreh F., Stegman, Melanie A., Ogden, Stacey K., Ascano, Manuel, Black, Kendall E., Tacchelly, Ofelia, Robbins, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781433/
https://ncbi.nlm.nih.gov/pubmed/19717563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041608
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