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Control of Cyclin-Dependent Kinase Inhibitor p27 Expression by Cap-Independent Translation

p27 is a key regulator of cell proliferation through inhibition of G(1) cyclin-dependent kinase (CDK) activity. Translation of the p27 mRNA is an important control mechanism for determining cellular levels of the inhibitor. Nearly all eukaryotic mRNAs are translated through a mechanism involving rec...

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Detalles Bibliográficos
Main Authors: Miskimins, W. Keith, Wang, Gang, Hawkinson, Michelle, Miskimins, Robin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC87223/
https://ncbi.nlm.nih.gov/pubmed/11438653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4960-4967.2001
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