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Control of Cyclin-Dependent Kinase Inhibitor p27 Expression by Cap-Independent Translation
p27 is a key regulator of cell proliferation through inhibition of G(1) cyclin-dependent kinase (CDK) activity. Translation of the p27 mRNA is an important control mechanism for determining cellular levels of the inhibitor. Nearly all eukaryotic mRNAs are translated through a mechanism involving rec...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87223/ https://ncbi.nlm.nih.gov/pubmed/11438653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4960-4967.2001 |
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