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Negative Regulation of CD4 Gene Expression by a HES-1–c-Myb Complex
Expression of the CD4 gene is tightly controlled throughout thymopoiesis. The downregulation of CD4 gene expression in CD4(−) CD8(−) and CD4(−) CD8(+) T lymphocytes is controlled by a transcriptional silencer located in the first intron of the CD4 locus. Here, we determine that the c-Myb transcripti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86935/ https://ncbi.nlm.nih.gov/pubmed/11287612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3071-3082.2001 |
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