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The Notch Pathway Intermediate HES-1 Silences CD4 Gene Expression

We have previously identified a transcriptional silencer that is critical for proper expression of the CD4 gene during T-cell development. Here we report that the Hairy/Enhancer of Split homologue HES-1, a transcription factor in the lin12/Notch signaling pathway, binds to an important functional si...

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Autori principali: Kim, Han K., Siu, Gerald
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109298/
https://ncbi.nlm.nih.gov/pubmed/9819403
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