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The Notch Pathway Intermediate HES-1 Silences CD4 Gene Expression

We have previously identified a transcriptional silencer that is critical for proper expression of the CD4 gene during T-cell development. Here we report that the Hairy/Enhancer of Split homologue HES-1, a transcription factor in the lin12/Notch signaling pathway, binds to an important functional si...

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Pubblicato in:Mol Cell Biol
Autori principali: Kim, Han K., Siu, Gerald
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.7166
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