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A Novel Yeast U2 snRNP Protein, Snu17p, Is Required for the First Catalytic Step of Splicing and for Progression of Spliceosome Assembly

We have isolated and microsequenced Snu17p, a novel yeast protein with a predicted molecular mass of 17 kDa that contains an RNA recognition motif. We demonstrate that Snu17p binds specifically to the U2 small nuclear ribonucleoprotein (snRNP) and that it is part of the spliceosome, since the pre-mR...

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Published in:Mol Cell Biol
Main Authors: Gottschalk, Alexander, Bartels, Cornelia, Neubauer, Gitte, Lührmann, Reinhard, Fabrizio, Patrizia
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2001
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.3037-3046.2001
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