Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
The DEAH-box helicase Prp43 is a key player in pre-mRNA splicing as well as the maturation of rRNAs. The exact modus operandi of Prp43 and of all other spliceosomal DEAH-box RNA helicases is still elusive. Here, we report crystal structures of Prp43 complexes in different functional states and the a...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications Ltd
2017-01-01
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| coleção: | eLife |
| Assuntos: | |
| Acesso em linha: | https://elifesciences.org/articles/21510 |
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