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Serum Response Factor Is Required for Immediate-Early Gene Activation yet Is Dispensable for Proliferation of Embryonic Stem Cells

Addition of serum to mitogen-starved cells activates the cellular immediate-early gene (IEG) response. Serum response factor (SRF) contributes to such mitogen-stimulated transcriptional induction of many IEGs during the G(0)-G(1) cell cycle transition. SRF is also believed to be essential for cell c...

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Autors principals: Schratt, Gerhard, Weinhold, Birgit, Lundberg, Ante S., Schuck, Sebastian, Berger, Jürgen, Schwarz, Heinz, Weinberg, Robert A., Rüther, Ulrich, Nordheim, Alfred
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86921/
https://ncbi.nlm.nih.gov/pubmed/11283270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2933-2943.2001
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