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Srf(–/–) ES cells display non-cell-autonomous impairment in mesodermal differentiation
The serum response factor (SRF) transcription factor is essential for murine embryogenesis. Srf(–/–) embryos stop developing at the onset of gastrulation, lacking detectable mesoderm. This developmental defect may reflect cell-autonomous impairment of Srf(–/–) embryonic cells in mesoderm formation....
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305791/ https://ncbi.nlm.nih.gov/pubmed/11060034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5835 |
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