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Reconstitution of Human β-Globin Locus Control Region Hypersensitive Sites in the Absence of Chromatin Assembly
The human β-globin genes are regulated by the locus control region (LCR), an element composed of multiple DNase I-hypersensitive sites (HS sites) located 5′ to the genes. Various functional studies indicate that the LCR confers high-level, position-independent, and copy number-dependent expression t...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86894/ https://ncbi.nlm.nih.gov/pubmed/11283243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2629-2640.2001 |
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