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Acetylation of a Specific Promoter Nucleosome Accompanies Activation of the ɛ-Globin Gene by β-Globin Locus Control Region HS2

On stably replicating episomes, transcriptional activation of the ɛ-globin promoter by the β-globin locus control region HS2 enhancer is correlated with an increase in nuclease sensitivity which is limited to the TATA-proximal nucleosome (N1). To elucidate what underlies this increase in nuclease se...

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Autori principali: Gui, Chang-Yun, Dean, Ann
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC99569/
https://ncbi.nlm.nih.gov/pubmed/11158302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.4.1155-1163.2001
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