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Apoptosis Suppression by Raf-1 and MEK1 Requires MEK- and Phosphatidylinositol 3-Kinase-Dependent Signals

Two Ras effector pathways leading to the activation of Raf-1 and phosphatidylinositol 3-kinase (PI3K) have been implicated in the survival signaling by the interleukin 3 (IL-3) receptor. Analysis of apoptosis suppression by Raf-1 demonstrated the requirement for mitochondrial translocation of the ki...

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Udgivet i:Mol Cell Biol
Principais autores: von Gise, Alexander, Lorenz, Petra, Wellbrock, Claudia, Hemmings, Brian, Berberich-Siebelt, Friederike, Rapp, Ulf R., Troppmair, Jakob
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.7.2324-2336.2001
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