Association of Insulin Receptor Substrate 1 (IRS-1) Y895 with Grb-2 Mediates the Insulin Signaling Involved in IRS-1-Deficient Brown Adipocyte Mitogenesis

We have recently generated immortalized fetal brown adipocyte cell lines from insulin receptor substrate 1 (IRS-1) knockout mice and demonstrated an impairment in insulin-induced lipid synthesis as compared to wild-type cell lines. In this study, we investigated the consequences of IRS-1 deficiency...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Valverde, Angela M., Mur, Cecilia, Pons, Sebastián, Alvarez, Alberto M., White, Morris F., Kahn, C. Ronald, Benito, Manuel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11259577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.7.2269-2280.2001
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