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Disruption of the Mouse μ-Calpain Gene Reveals an Essential Role in Platelet Function

Conventional calpains are ubiquitous calcium-regulated cysteine proteases that have been implicated in cytoskeletal organization, cell proliferation, apoptosis, cell motility, and hemostasis. There are two forms of conventional calpains: the μ-calpain, or calpain I, which requires micromolar calcium...

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Bibliografiske detaljer
Main Authors: Azam, Mohammad, Andrabi, Shaida S., Sahr, Kenneth E., Kamath, Lakshmi, Kuliopulos, Athan, Chishti, Athar H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86855/
https://ncbi.nlm.nih.gov/pubmed/11238954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2213-2220.2001
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